Disease-A-Month
Volume 49, Issue 1 , Pages 14-21 , January 2003

The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis

References 

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  2. Baglia FA, Walsh PN. Prothrombin is a cofactor for the binding of factor XI to the platelet surface and for platelet-mediated factor XI activation by thrombin. Biochemistry. 1998;37:2271–2281
  3. Davie EW, Ratnoff OD. Waterfall sequence for intrinsic blood clotting. Science. 1964;145:1310–1312
  4. Gailani D, Broze GJ. Factor XI activation in a revised model of blood coagulation. Science. 1991;253:909–912
  5. Hoffman M, Monroe DM, Roberts HR. Activated factor VII activates factors IX and X on the surface of activated platelets: Thoughts on the mechanism of action of high-dose activated factor VII. Blood Coagul Fibrinolysis. 1998;9:S61–S65
  6. Hoffman M, Monroe DM, Oliver JA, et al.  Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation. Blood. 1995;86:1794–1801
  7. Monroe DM, Hoffman M, Oliver JA, et al.  A possible mechanism of action of activated factor VII independent of tissue factor. Blood Coagul Fibrinolysis. 1998;9(suppl):S15–S20
  8. Nemerson Y, Esnouf MP. Activation of a proteolytic system by a membrane lipoprotein: Mechanism of action of tissue factor. Proc Natl Acad Sci USA. 1973;70:310–314
  9. Nemerson Y. The tissue factor pathway of blood coagulation. Semin Hematol. 1992;29:170–176
  10. Oliver J, Monroe D, Roberts H, et al.  Thrombin activates factor XI on activated platelets in the absence of factor XII. Arterioscler Thromb Vasc Biol. 1999;19:170–177
  11. Østerud B, Rapaport SI. Activation of factor IX by the reaction product of tissue factor and factor VII: Additional pathway for initiating blood coagulation. Proc Natl Acad Sci USA. 1977;74:5260–5264
  12. Repke D, Gemmell CH, Guha A, et al.  Hemophilia as a defect of the tissue factor pathway of blood coagulation: Effect of factors VIII and IX on factor X activation in a continuous-flow reactor. Proc Natl Acad Sci USA. 1990;87:7623–7627
  13. van't Veer C, Golden NJ, Mann KG. Inhibition of thrombin generation by the zymogen factor VII: Implications for the treatment of hemophilia A by factor VIIa. Blood. 2000;95:1330–1335

PII: S0011-5029(03)90011-3

doi: 10.1016/S0011-5029(03)90011-3

Disease-A-Month
Volume 49, Issue 1 , Pages 14-21 , January 2003

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